Issue 26, 2011
From the journal:

Chemical Communications

A V-shaped cationic dye for nonlinear optical bioimaging†

Ermelinda Maçôas,*a   Gema Marcelo,‡a   Sandra Pinto,a   Tatiana Cañeque,b   Ana M. Cuadro,b   Juan J. Vaquerob  and  José M. G. Martinhoa  

* Corresponding authors

a Centro de Química-Física Molecular (CQFM) and Institute of Nanoscience and Nanotechnology (IN), Instituto Superior Técnico, 1049-001 Lisboa, Portugal
E-mail: ermelinda.macoas@ist.utl.pt
Fax: +351 218419218
Tel: +351 218464455

b Departamento de Química Orgánica, Universidad de Alcalá, 28871-Alcalá de Henares, Madrid, Spain

Abstract

A symmetric cationic molecule with D-π-A+-π-D architecture was synthesized with high two-photon absorption cross-section (σ2 ≈ 1140 GM). Application as a marker in fluorescence microscopy of living cells revealed its presence inside the cell staining vesicular shape organelles in the cytoplasm. Fluorescence lifetime imaging microscopy shows that it is also able to penetrate within the nucleus.

Graphical abstract: A V-shaped cationic dye for nonlinear optical bioimaging

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Article information

DOI
https://doi.org/10.1039/C1CC12163D
Article type
Communication
Submitted
14 Apr 2011
Accepted
13 May 2011
First published
27 May 2011

Chem. Commun., 2011,47, 7374-7376

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A V-shaped cationic dye for nonlinear optical bioimaging

E. Maçôas, G. Marcelo, S. Pinto, T. Cañeque, A. M. Cuadro, J. J. Vaquero and J. M. G. Martinho, Chem. Commun., 2011, 47, 7374 DOI: 10.1039/C1CC12163D

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