Issue 26, 2011

Facile functionalization of polypeptides by thiol-yne photochemistry for biomimetic materials synthesis

Abstract

Rapid and highly efficient side-chain functionalization of polypeptides was achieved via combination of ring-opening polymerization of a new clickable monomer of γ-propargyl-L-glutamateN-carboxyanhydride (PLG-NCA) and thiol-yne photochemistry, which provides a convenient and universal route to prepare diverse polypeptide-based biomimetic hybrid materials.

Graphical abstract: Facile functionalization of polypeptides by thiol-yne photochemistry for biomimetic materials synthesis

Supplementary files

Article information

Article type
Communication
Submitted
15 Apr 2011
Accepted
16 May 2011
First published
31 May 2011

Chem. Commun., 2011,47, 7509-7511

Facile functionalization of polypeptides by thiol-yne photochemistry for biomimetic materials synthesis

Y. Huang, Y. Zeng, J. Yang, Z. Zeng, F. Zhu and X. Chen, Chem. Commun., 2011, 47, 7509 DOI: 10.1039/C1CC12177D

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