Issue 29, 2011
From the journal:

Chemical Communications

Highly enhanced electrochemiluminescence based on synergetic catalysis effect of enzyme and Pd nanoparticles for ultrasensitive immunoassay†

Huan Niu,a   Ruo Yuan,*a   Yaqin Chai,*a   Li Mao,a   Yali Yuan,a   Yaling Caoa  and  Ying Zhuoa  

* Corresponding authors

a Education Ministry Key Laboratory on Luminescence and Real-Time Analysis, College of Chemistry and Chemical Engineering, Chongqing 400715, People's Republic of China
E-mail: jessie1516@163.com, yuanruo@swu.edu.cn
Fax: +86 23 68254000
Tel: +86 23 68252277

Abstract

An immunosensor based on the electrochemiluminescence (ECL) of luminol was proposed by coupling enzymatic reaction to in situ generate coreactant with Pd nanoparticles as catalyst for the ECL reaction, which was successfully applied for the ultrasensitive detection of α-1-fetoprotein with a low detection limit of 33 fg mL−1.

Graphical abstract: Highly enhanced electrochemiluminescence based on synergetic catalysis effect of enzyme and Pd nanoparticles for ultrasensitive immunoassay

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Article information

DOI
https://doi.org/10.1039/C1CC12179K
Article type
Communication
Submitted
15 Apr 2011
Accepted
08 Jun 2011
First published
24 Jun 2011

Chem. Commun., 2011,47, 8397-8399

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Highly enhanced electrochemiluminescence based on synergetic catalysis effect of enzyme and Pd nanoparticles for ultrasensitive immunoassay

H. Niu, R. Yuan, Y. Chai, L. Mao, Y. Yuan, Y. Cao and Y. Zhuo, Chem. Commun., 2011, 47, 8397 DOI: 10.1039/C1CC12179K

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