Issue 29, 2011
From the journal:

Chemical Communications

A highly selective space-folded photo-induced electron transferfluorescent probe for carbonic anhydrase isozymes IX and its applications for biological imaging†

Shenyi Zhang,a   Chunmei Yang,a   Weiqiang Lu,a   Jin Huang,a   Weiping Zhu,a   Honglin Li,a   Yufang Xu*a  and  Xuhong Qian*a  

* Corresponding authors

a State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of Chemical Biology, School of Pharmacy East China University of Science and Technology, Meilong Road 130, Shanghai, 200237, China
E-mail: yfxu@ecust.edu.cn, xhqian@ecust.edu.cn
Fax: +86 21-64252603

Abstract

The first highly selective and sensitive fluorescent probe Z1 for detection of carbonic anhydrase IX (CA IX) over isoforms CA I and CA II was developed. As demonstrated, Z1 worked effectively in both enzymatic systems and living hypoxia cells.

Graphical abstract: A highly selective space-folded photo-induced electron transfer fluorescent probe for carbonic anhydrase isozymes IX and its applications for biological imaging

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Article information

DOI
https://doi.org/10.1039/C1CC12386F
Article type
Communication
Submitted
24 Apr 2011
Accepted
31 May 2011
First published
17 Jun 2011

Chem. Commun., 2011,47, 8301-8303

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A highly selective space-folded photo-induced electron transfer fluorescent probe for carbonic anhydrase isozymes IX and its applications for biological imaging

S. Zhang, C. Yang, W. Lu, J. Huang, W. Zhu, H. Li, Y. Xu and X. Qian, Chem. Commun., 2011, 47, 8301 DOI: 10.1039/C1CC12386F

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