Issue 27, 2011
From the journal:

Chemical Communications

Thiourea isosteres as anion receptors and transmembrane transporters†

Marco Wenzel,a   Mark E. Light,a   Anthony P. Davisb  and  Philip A. Gale*a  

* Corresponding authors

a Chemistry, University of Southampton, Southampton, UK
E-mail: philip.gale@soton.ac.uk
Fax: +44 (0)23 8059 6805
Tel: + 44 (0)23 8059 3332

b School of Chemistry, University of Bristol, Cantock's Close, Bristol, UK
E-mail: anthony.davis@bristol.ac.uk

Abstract

Compounds containing cyanoguanidine and 3-amino-1,2,4-benzothiadiazine-1,1-dioxide have been studied as anion receptors and transporters. Significant affinity for oxo-anions was observed in organic solution and the receptors were found to function as transmembrane chloride/nitrate antiporters with transport rates enhanced in the presence of valinomycin–K+ complex.

Graphical abstract: Thiourea isosteres as anion receptors and transmembrane transporters

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Article information

DOI
https://doi.org/10.1039/C1CC12439K
Article type
Communication
Submitted
26 Apr 2011
Accepted
24 May 2011
First published
09 Jun 2011

Chem. Commun., 2011,47, 7641-7643

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Thiourea isosteres as anion receptors and transmembrane transporters

M. Wenzel, M. E. Light, A. P. Davis and P. A. Gale, Chem. Commun., 2011, 47, 7641 DOI: 10.1039/C1CC12439K

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