Issue 29, 2011

Catalytic decarboxylative alkylation of β-keto acids with sulfonamidesvia the cleavage of carbon–nitrogen and carbon–carbon bonds

Abstract

An efficient decarboxylative alkylation reaction of β-keto acids with N-benzylic or N-allylic sulfonamides has been developed, for the first time, through sequential cleavage of carbon–nitrogen and carbon–carbon bonds in the presence of 10 mol% of FeCl3.

Graphical abstract: Catalytic decarboxylative alkylation of β-keto acids with sulfonamidesvia the cleavage of carbon–nitrogen and carbon–carbon bonds

Supplementary files

Article information

Article type
Communication
Submitted
12 May 2011
Accepted
07 Jun 2011
First published
22 Jun 2011

Chem. Commun., 2011,47, 8343-8345

Catalytic decarboxylative alkylation of β-keto acids with sulfonamidesvia the cleavage of carbon–nitrogen and carbon–carbon bonds

C. Yang, J. Wang and S. Tian, Chem. Commun., 2011, 47, 8343 DOI: 10.1039/C1CC12790J

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