Issue 33, 2011
From the journal:

Chemical Communications

Metal-free intramolecular oxidative decarboxylative amination of primary α-amino acids with product selectivity†

Yizhe Yana  and  Zhiyong Wang*a  

* Corresponding authors

a Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Soft Matter Chemistry and Department of Chemistry, University of Science and Technology of China, Hefei, P. R. China
E-mail: zwang3@ustc.edu.cn
Fax: (+86) 551-360-3185

Abstract

A novel metal-free intramolecular oxidative decarboxylative coupling of primary α-amino acids with 2-aminobenzoketones under mild and neutral conditions was developed. Different quinazolines can be selectively obtained by various oxidants.

Graphical abstract: Metal-free intramolecular oxidative decarboxylative amination of primary α-amino acids with product selectivity

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Article information

DOI
https://doi.org/10.1039/C1CC12885J
Article type
Communication
Submitted
17 May 2011
Accepted
20 Jun 2011
First published
19 Jul 2011

Chem. Commun., 2011,47, 9513-9515

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Metal-free intramolecular oxidative decarboxylative amination of primary α-amino acids with product selectivity

Y. Yan and Z. Wang, Chem. Commun., 2011, 47, 9513 DOI: 10.1039/C1CC12885J

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