Issue 37, 2011
From the journal:

Chemical Communications

Superquencher formation vianucleic acid induced noncovalent perylene probe self-assembly†

Bin Wang,‡ab   Huping Jiao,‡ab   Wenying Li,ab   Dongli Liao,ab   Fangyuan Wangab  and  Cong Yu*ab  

* Corresponding authors

a State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China

b Graduate School of the Chinese Academy of Sciences, Beijing 100039, P. R. China
E-mail: congyu@ciac.jl.cn
Fax: +86 431-8526-2710

Abstract

A fluorophore labeled oligonucleotide could induce aggregation of a positively charged perylene probe. The perylene aggregate could very efficiently quench the fluorescence of the labeled fluorophore. Based on this observation, a new method for the highly sensitive and selective detection of a protein has been developed.

Graphical abstract: Superquencher formation vianucleic acid induced noncovalent perylene probe self-assembly

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Article information

DOI
https://doi.org/10.1039/C1CC13606B
Article type
Communication
Submitted
17 Jun 2011
Accepted
03 Aug 2011
First published
22 Aug 2011

Chem. Commun., 2011,47, 10269-10271

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Superquencher formation vianucleic acid induced noncovalent perylene probe self-assembly

B. Wang, H. Jiao, W. Li, D. Liao, F. Wang and C. Yu, Chem. Commun., 2011, 47, 10269 DOI: 10.1039/C1CC13606B

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