Issue 35, 2011
From the journal:

Chemical Communications

A fluorescent turn-on probe for the detection of alkaline phosphatase activity in living cells†

Tae-Il Kim,‡a   Hyunjin Kim,‡b   Yongdoo Choi*b  and  Youngmi Kim*a  

* Corresponding authors

a Department of Chemistry, Dankook University, 126 Jukjeon-dong, Yongin-si, Gyeonggi-do, Korea
E-mail: youngmi@dankook.ac.kr
Fax: +8231-8005-3148
Tel: +8231-8005-3156

b Molecular Imaging & Therapy Branch, National Cancer Center, 323 Ilsan-ro, Goyang-si, Gyeonggi-do, Korea
E-mail: ydchoi@ncc.re.kr
Fax: +8231-920-2529
Tel: +8231-920-2512

Abstract

Fluorescent probe 1, showing a high fluorescence turn-on signal ratio, enables the real-time imaging of endogenous alkaline phosphatase (ALP) activity in living cells, and the fast and quantitative analysis of enzyme activity at the single-cell level.

Graphical abstract: A fluorescent turn-on probe for the detection of alkaline phosphatase activity in living cells

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Article information

DOI
https://doi.org/10.1039/C1CC13819G
Article type
Communication
Submitted
27 Jun 2011
Accepted
21 Jul 2011
First published
05 Aug 2011

Chem. Commun., 2011,47, 9825-9827

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A fluorescent turn-on probe for the detection of alkaline phosphatase activity in living cells

T. Kim, H. Kim, Y. Choi and Y. Kim, Chem. Commun., 2011, 47, 9825 DOI: 10.1039/C1CC13819G

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