Issue 38, 2011
From the journal:

Chemical Communications

Kinetically grafting G-quadruplexes onto DNA nanostructures for structure and function encoding via a DNA machine†

Jiangtao Ren,ab   Jiahai Wang,*a   Lei Han,ab   Erkang Wang*a  and  Jin Wang*ac  

* Corresponding authors

a State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Changchun, Jilin, China
E-mail: jhwang@ciac.jl.cn, ekwang@ciac.jl.cn, jin.wang.1@stonybrook.edu
Fax: +86-431-85689711
Tel: +86-431-85262003

b Graduate School of Chinese Academy of Science, Beijing, China

c Department of Chemistry and Physics, State University of New York at Stony Brook, New York, USA

Abstract

Kinetically grafting G-quadruplexes onto one-dimensional DNA nanostructures with precise positioning was realized in this study. The programs hold great promise for label-free and enzyme-free detection of various targets as a result of signal amplification from G-quadruplexes, and building DNA nanostructures as scaffolds due to the molecular recognition capacity of G-quadruplex aptamers.

Graphical abstract: Kinetically grafting G-quadruplexes onto DNA nanostructures for structure and function encoding via a DNA machine

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Article information

DOI
https://doi.org/10.1039/C1CC13973H
Article type
Communication
Submitted
04 Jul 2011
Accepted
29 Jul 2011
First published
22 Aug 2011

Chem. Commun., 2011,47, 10563-10565

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Kinetically grafting G-quadruplexes onto DNA nanostructures for structure and function encoding via a DNA machine

J. Ren, J. Wang, L. Han, E. Wang and J. Wang, Chem. Commun., 2011, 47, 10563 DOI: 10.1039/C1CC13973H

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