Issue 40, 2011
From the journal:

Chemical Communications

Combination of π–π stacking and electrostatic repulsion between carboxylic carbon nanoparticles and fluorescent oligonucleotides for rapid and sensitive detection of thrombin†

Jinhua Liu,a   Jishan Li,a   Ying Jiang,a   Sheng Yang,a   Weihong Tana  and  Ronghua Yang*a  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Chan, China
E-mail: Yangrh@pku.edu.cn

Abstract

On the basis of simultaneous electrostatic repulsion and π–π stacking interactions of carboxylic carbon nanoparticles (cCNPs) with single-stranded DNA, a noncovalent assembly of cCNPs and fluorescent aptamers is reported for rapid, sensitive, and selective detection of thrombin.

Graphical abstract: Combination of π–π stacking and electrostatic repulsion between carboxylic carbon nanoparticles and fluorescent oligonucleotides for rapid and sensitive detection of thrombin

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Article information

DOI
https://doi.org/10.1039/C1CC14445F
Article type
Communication
Submitted
21 Jul 2011
Accepted
02 Sep 2011
First published
15 Sep 2011

Chem. Commun., 2011,47, 11321-11323

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Combination of π–π stacking and electrostatic repulsion between carboxylic carbon nanoparticles and fluorescent oligonucleotides for rapid and sensitive detection of thrombin

J. Liu, J. Li, Y. Jiang, S. Yang, W. Tan and R. Yang, Chem. Commun., 2011, 47, 11321 DOI: 10.1039/C1CC14445F

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