Issue 44, 2011

Identification of γ-AApeptides with potent and broad-spectrum antimicrobial activity

Abstract

We report the identification of a new class of antimicrobial peptidomimetics-γ-AApeptides with potent and broad-spectrum activity, including clinically-relevant strains that are unresponsive to most antibiotics. They are also not prone to select for drug-resistance.

Graphical abstract: Identification of γ-AApeptides with potent and broad-spectrum antimicrobial activity

Supplementary files

Article information

Article type
Communication
Submitted
22 Jul 2011
Accepted
19 Sep 2011
First published
03 Oct 2011

Chem. Commun., 2011,47, 12197-12199

Identification of γ-AApeptides with potent and broad-spectrum antimicrobial activity

Y. Niu, S. Padhee, H. Wu, G. Bai, L. Harrington, W. N. Burda, L. N. Shaw, C. Cao and J. Cai, Chem. Commun., 2011, 47, 12197 DOI: 10.1039/C1CC14476F

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