Ag        cluster–aptamer hybrid: specifically marking the nucleus of live cells

Zhipeng Sun; Yaling Wang; Yueteng Wei; Ru Liu; Huarui Zhu; Yanyan Cui; Yuliang Zhao; Xueyun Gao

doi:10.1039/C1CC14652A

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Ag cluster–aptamer hybrid: specifically marking the nucleus of live cells†

Zhipeng Sun,^a Yaling Wang,^a Yueteng Wei,^a Ru Liu,^a Huarui Zhu,^a Yanyan Cui,^a Yuliang Zhao^a and Xueyun Gao*^a

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* Corresponding authors

^a Institute of High Energy Physics, Chinese Academy of Sciences, Yuquan Road 19B, Beijing 10049, Shi Jing Shan District, China
E-mail: gaoxy@ihep.ac.cn
Fax: +86-10-88236456
Tel: +86-10-88236709

Abstract

Silver cluster–aptamer hybrids were mineralized via an artificially designed aptamer. The hybrids gave red emission when excited by light, and they successfully targeted the nucleus of live cells. This method is an effective approach to make cell target probes.

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Article information

DOI: https://doi.org/10.1039/C1CC14652A
Article type: Communication
Submitted: 29 Jul 2011
Accepted: 20 Sep 2011
First published: 30 Sep 2011

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Chem. Commun., 2011,47, 11960-11962

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Ag cluster–aptamer hybrid: specifically marking the nucleus of live cells

Z. Sun, Y. Wang, Y. Wei, R. Liu, H. Zhu, Y. Cui, Y. Zhao and X. Gao, Chem. Commun., 2011, 47, 11960 DOI: 10.1039/C1CC14652A

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Chemical Communications