Issue 38, 2011
From the journal:

Physical Chemistry Chemical Physics

A protic ionic liquid attenuates the deleterious actions of urea on α-chymotrypsin†

Pankaj Attri,a   Pannuru Venkatesu,*a   Anil Kumarb  and  Nolene Byrnec  

* Corresponding authors

a Department of Chemistry, University of Delhi, Delhi – 110 007, India
E-mail: venkatesup@hotmail.com, pvenkatesu@chemistry.du.ac.in
Fax: +91-11-2766 6605

b Physical Chemistry Division, National Chemical Laboratory, Pune-411 008, India
E-mail: a.kumar@ncl.res.in

c Institute for Technology Research and Innovation, Deakin University, Geelong, Australia

Abstract

We present a biocompatible ionic liquid, triethyl ammonium acetate (TEAA), that attenuates the denaturation action of a non-ionic chaotrope, urea, on the industrially relevant proteolytic enzyme α-chymotrypsin.

Graphical abstract: A protic ionic liquid attenuates the deleterious actions of urea on α-chymotrypsin

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Article information

DOI
https://doi.org/10.1039/C1CP22195G
Article type
Communication
Submitted
04 Jul 2011
Accepted
19 Aug 2011
First published
01 Sep 2011

Phys. Chem. Chem. Phys., 2011,13, 17023-17026

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A protic ionic liquid attenuates the deleterious actions of urea on α-chymotrypsin

P. Attri, P. Venkatesu, A. Kumar and N. Byrne, Phys. Chem. Chem. Phys., 2011, 13, 17023 DOI: 10.1039/C1CP22195G

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