Issue 9, 2011
From the journal:

Chemical Society Reviews

Divergent reactions on racemic mixtures

Laura C. Millera  and  Richmond Sarpong*b  

* Corresponding authors

a Department of Chemistry, Princeton University, Princeton, USA

b Department of Chemistry, University of California, Berkeley, California 94720, USA
E-mail: rsarpong@berkeley.edu

Abstract

Methods that furnish enantioenriched products are crucial in modern organic synthesis. An underutilized strategy to arrive at enantioenriched products is to perform divergent reactions on racemic mixtures, where each enantiomer of the starting material reacts with a single chiral reagent to furnish two separable, non-enantiomeric products that are enantioenriched. Stereodivergent, regiodivergent and structurally divergent reactions on racemic mixtures are discussed in this tutorial review.

Graphical abstract: Divergent reactions on racemic mixtures

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Article information

DOI
https://doi.org/10.1039/C1CS15069C
Article type
Tutorial Review
Submitted
16 Mar 2011
First published
31 May 2011

Chem. Soc. Rev., 2011,40, 4550-4562

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Divergent reactions on racemic mixtures

L. C. Miller and R. Sarpong, Chem. Soc. Rev., 2011, 40, 4550 DOI: 10.1039/C1CS15069C

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