Issue 18, 2011
From the journal:

Dalton Transactions

Synthesis of multifunctional Fe3O4 core/hydroxyapatite shell nanocomposites by biomineralization

Chi Huang,a   Yangbo Zhou,b   Zhaomin Tang,b   Xing Guo,b   Zhiyong Qianc  and  Shaobing Zhou*ab  

* Corresponding authors

a School of Materials Science and Engineering, Key Laboratory of Advanced Technologies of Materials, Ministry of Education, Southwest Jiaotong University, Chengdu, P. R. China
E-mail: shaobingzhou@hotmail.com;shaobingzhou@swjtu.edu.cn
Fax: +86 2887634649
Tel: +86 2887634023

b School of Life Science and Engineering, Southwest Jiaotong University, Chengdou, P.R. China

c State Key Laboratory of Biotherapy, West China Hospital, West China Medicine School, Sichuan University, Chengdu, China

Abstract

Superparamagnetic nanoparticles with surface functional groups (–OH, –COOH and –NH2) were modified by in situ deposition of hydroxyapatite (HA) on the materials' surface through the biomineralization process to form Fe3O4 core/hydroxyapatite shell nanocomposites. They possess potential applications as targeted carriers for antitumor drugs and as bone tissue engineering scaffolds by integrating multiple functions into a single nanosystem.

Graphical abstract: Synthesis of multifunctional Fe3O4 core/hydroxyapatite shell nanocomposites by biomineralization

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Article information

DOI
https://doi.org/10.1039/C0DT01824D
Article type
Paper
Submitted
24 Dec 2010
Accepted
10 Mar 2011
First published
31 Mar 2011

Dalton Trans., 2011,40, 5026-5031

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Synthesis of multifunctional Fe3O4 core/hydroxyapatite shell nanocomposites by biomineralization

C. Huang, Y. Zhou, Z. Tang, X. Guo, Z. Qian and S. Zhou, Dalton Trans., 2011, 40, 5026 DOI: 10.1039/C0DT01824D

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