Pyridinium derivatives of histamine are potent activators of cytosolic carbonic anhydrase isoforms I, II and VII†
Abstract
A series of positively-charged derivatives has been prepared by reaction of
* Corresponding authors
a
Temple University School of Pharmacy, Department of Pharmaceutical Sciences, 3307 North Broad Street, Philadelphia, USA
E-mail:
mailies@temple.edu
Fax: +1-215-707-5620
Tel: +1-215-707-1749
b Moulder Center for Drug Discovery Research, Temple University, 3307 North Broad Street, Philadelphia, USA
c
Università degli Studi, Department of Chemistry Ugo Schiff, Laboratory of Bioinorganic Chemistry, Via della Lastruccia 3, Polo Scientifico, 50019-Sesto Fiorentino (Florence), Italy
E-mail:
claudiu.supuran@unifi.it
Fax: +39-055-4573385
Tel: +39-055-4573005
A series of positively-charged derivatives has been prepared by reaction of
K. Dave, A. Scozzafava, D. Vullo, C. T. Supuran and M. A. Ilies, Org. Biomol. Chem., 2011, 9, 2790 DOI: 10.1039/C0OB00703J
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