Issue 5, 2011

Asymmetric synthesis of 1-deoxyazasugars from chiral aziridines

Abstract

A general and facile synthesis of enantiopure 1-deoxyazasugars was achieved from stereoselective dihydroxylation of a common synthetic intermediate, piperidine ring fused oxazolidin-2-one, originating from a commercially available starting substrate, chiral aziridine-2-carboxylate, in high yields.

Graphical abstract: Asymmetric synthesis of 1-deoxyazasugars from chiral aziridines

Supplementary files

Article information

Article type
Paper
Submitted
16 Sep 2010
Accepted
03 Nov 2010
First published
04 Nov 2010

Org. Biomol. Chem., 2011,9, 1372-1380

Asymmetric synthesis of 1-deoxyazasugars from chiral aziridines

A. Singh, B. Kim, W. K. Lee and H. Ha, Org. Biomol. Chem., 2011, 9, 1372 DOI: 10.1039/C0OB00730G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements