Issue 7, 2011

A methionine-based turn-on chemical sensor for selectively monitoring Hg2+ ions in 100% aqueous solution

Abstract

Dansyl-labeled methionine is synthesized by solid-phase synthesis, and found to be a highly sensitive and selective sensor for Hg2+. The sensor sensitively detects Hg2+ ions in aqueous solution by a turn-on response; however, the sensor detects Hg2+ ions by a turn-off response in organic and mixed aqueous–organic solutions. We investigated the binding stoichiometry, binding constant, and binding mode of the sensor under various solvent conditions. In 100% aqueous solution, 2 : 1 complexation of the sensor with Hg2+ ions is more favorable than 1 : 1 complexation, whereas the sensor preferentially forms a 1 : 1 complex in 100% CH3CN or in 50% CH3CN–aqueous solutions. Results reveal that the stoichiometry of the sensor–Hg2+ complex plays an important role in the type of response to Hg2+ ions, and that 2 : 1 complexation is required for a turn-on response to Hg2+ ions in aqueous solution.

Graphical abstract: A methionine-based turn-on chemical sensor for selectively monitoring Hg2+ ions in 100% aqueous solution

Supplementary files

Article information

Article type
Paper
Submitted
25 Sep 2010
Accepted
13 Dec 2010
First published
11 Feb 2011

Org. Biomol. Chem., 2011,9, 2350-2356

A methionine-based turn-on chemical sensor for selectively monitoring Hg2+ ions in 100% aqueous solution

M. Yang, C. R. Lohani, H. Cho and K. Lee, Org. Biomol. Chem., 2011, 9, 2350 DOI: 10.1039/C0OB00780C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements