A practical synthesis of Rho-Kinase inhibitor Y-27632 and fluoro derivatives and their evaluation in human pluripotent stem cells†
Abstract
A practical synthesis of the Rho-Kinase
* Corresponding authors
a
Institut für Organische Chemie and Biomolekulares Wirkstoffzentrum (BMWZ), Leibniz Universität Hannover, Schneiderberg 1b, Hannover, Germany
E-mail:
andreas.kirschning@oci.uni-hannover.de
Fax: +49 (0)511-7623011
Tel: +49 (0)511-7624614
b Hannover Medical School (MHH), Department of Cardiac, Thoracic, Transplantation and Vascular surgery (HTTG), Leibniz research laboratories for biotechnology and artificial organs (LEBAO), Carl-Neuberg-Str. 1, Hannover, Germany
A practical synthesis of the Rho-Kinase
J. Paleček, R. Zweigerdt, R. Olmer, U. Martin, A. Kirschning and G. Dräger, Org. Biomol. Chem., 2011, 9, 5503 DOI: 10.1039/C1OB05332A
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