Issue 23, 2011
From the journal:

Organic & Biomolecular Chemistry

A facile transformation of amino acids to functionalized coumarins†

Anupam Bandyopadhyaya  and  Hosahudya N. Gopi*a  

* Corresponding authors

a Department of Chemistry, Indian Institute of Science Education and Research, Garware Circle, Pashan, Pune 411021, India
E-mail: hn.gopi@iiserpune.ac.in
Fax: +91 (20) 2589 9790
Tel: +91 20 2590 8075

Abstract

The synthesis of novel chiral coumarins functionalized with proteinogenic amino acid side chains via N-protected γ-amino-β-keto esters and their incorporation into the cell permeable HIV-1 TAT peptide through the modified solid phase peptide synthesis are described.

Graphical abstract: A facile transformation of amino acids to functionalized coumarins

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Article information

DOI
https://doi.org/10.1039/C1OB05815K
Article type
Paper
Submitted
24 May 2011
Accepted
31 Aug 2011
First published
01 Sep 2011

Org. Biomol. Chem., 2011,9, 8089-8095

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A facile transformation of amino acids to functionalized coumarins

A. Bandyopadhyay and H. N. Gopi, Org. Biomol. Chem., 2011, 9, 8089 DOI: 10.1039/C1OB05815K

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