Issue 20, 2011
From the journal:

Organic & Biomolecular Chemistry

An aldol approach to the enantioselective synthesis of (−)-oseltamivir phosphate†

Milos Trajkovic,a   Zorana Ferjancic*a  and  Radomir N. Saicic*a  

* Corresponding authors

a Faculty of Chemistry, University of Belgrade, Studentski trg 16, 11158 Belgrade 118, P. O. B. 51, Serbia
E-mail: rsaicic@chem.bg.ac.rs, zferjan@chem.bg.ac.rs
Fax: +381 11 32 82 537.

Abstract

A formal asymmetric synthesis of the antiviral agent (−)-oseltamivir phosphate is achieved using two aldol reactions as key steps.

Graphical abstract: An aldol approach to the enantioselective synthesis of (−)-oseltamivir phosphate

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Article information

DOI
https://doi.org/10.1039/C1OB06248D
Article type
Communication
Submitted
25 Jul 2011
Accepted
16 Aug 2011
First published
16 Aug 2011

Org. Biomol. Chem., 2011,9, 6927-6929

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An aldol approach to the enantioselective synthesis of (−)-oseltamivir phosphate

M. Trajkovic, Z. Ferjancic and R. N. Saicic, Org. Biomol. Chem., 2011, 9, 6927 DOI: 10.1039/C1OB06248D

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