Issue 22, 2011
From the journal:

Organic & Biomolecular Chemistry

Chromo-fluorogenic detection of aldehydes with a rhodamine based sensor featuring an intramolecular deoxylactam†

Zhu Li,‡ab   Zhongwei Xue,‡a   Zhisheng Wu,a   Jiahuai Hanb  and  Shoufa Han*a  

* Corresponding authors

a Department of Chemical Biology, College of Chemistry and Chemical Engineering, and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, Xiamen, China

b State Key Laboratory of Cellular Stress Biology and School of Life Sciences, Xiamen University, Xiamen, China
E-mail: shoufa@xmu.edu.cn
Fax: +86-0592-2181728

Abstract

A chromogenic and fluorogenic detection of aldehydes was achieved viaanalyte triggered opening of the deoxylactam of N-(rhodamine B)-deoxylactam-ethylenediamine (dRB-EDA). The utility of the sensor was demonstrated by fluorescent labeling of aldehyde-displaying sialoproteins on cell surfaces.

Graphical abstract: Chromo-fluorogenic detection of aldehydes with a rhodamine based sensor featuring an intramolecular deoxylactam

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Article information

DOI
https://doi.org/10.1039/C1OB06448G
Article type
Communication
Submitted
24 Aug 2011
Accepted
14 Sep 2011
First published
14 Sep 2011

Org. Biomol. Chem., 2011,9, 7652-7654

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Chromo-fluorogenic detection of aldehydes with a rhodamine based sensor featuring an intramolecular deoxylactam

Z. Li, Z. Xue, Z. Wu, J. Han and S. Han, Org. Biomol. Chem., 2011, 9, 7652 DOI: 10.1039/C1OB06448G

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