Oligostilbenes from Vatica mangachapoi with xanthine oxidase and acetylcholinesterase inhibitory activities

Abstract

Phytochemical examination of the branches and twigs of the tropical plant Vatica mangachapoi resulted in the isolation of three novel oligostilbenes named vaticahainols A–C (1–3) along with seventeen known oligostilbenes (4–20). The structures of the new compounds were elucidated on the basis of extensive spectroscopic data analysis, modified Mosher's method, and quantum chemical computation. All of the isolated phytochemicals were screened for their xanthine oxidase (XO) and acetylcholinesterase (AChE) inhibitory activities.