Issue 5, 2012
From the journal:

Analyst

A label-free thrombin binding aptamer as a probe for highly sensitive and selective detection of lead(ii) ions by a resonance Rayleigh scattering method†

Xiao Bei Fu,a   Fei Qu,a   Nian Bing Li*a  and  Hong Qun Luo*a  

* Corresponding authors

a Education Ministry Key Laboratory on Luminescence and Real-Time Analysis, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China
E-mail: linb @swu.edu.cn, luohq @swu.edu.cn
Fax: +86 23-6825-3237
Tel: +86 23-6825-3237

Abstract

The binding of lead(II) ions with unusually high affinity to a thrombin binding aptamer resulted in an enhancement of resonance Rayleigh scattering (RRS). A simple, sensitive, and selective assay for the direct determination of trace amounts of Pb2+ on the basis of RRS has been proposed.

Graphical abstract: A label-free thrombin binding aptamer as a probe for highly sensitive and selective detection of lead(ii) ions by a resonance Rayleigh scattering method

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Article information

DOI
https://doi.org/10.1039/C2AN15980E
Article type
Communication
Submitted
19 Oct 2011
Accepted
11 Jan 2012
First published
25 Jan 2012

Analyst, 2012,137, 1097-1099

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A label-free thrombin binding aptamer as a probe for highly sensitive and selective detection of lead(II) ions by a resonance Rayleigh scattering method

X. B. Fu, F. Qu, N. B. Li and H. Q. Luo, Analyst, 2012, 137, 1097 DOI: 10.1039/C2AN15980E

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