Issue 4, 2012
From the journal:

Chemical Communications

Synthesis of novel lidocaine-releasing poly(diol-co-citrate) elastomers by using deep eutectic solvents†

M. Concepción Serrano,*a   María C. Gutiérrez,a   Ricardo Jiménez,a   M. Luisa Ferrera  and  Francisco del Monte*a  

* Corresponding authors

a Instituto de Ciencia de Materiales de Madrid (ICMM), Consejo Superior de Investigaciones Científicas (CSIC), Cantoblanco 28049, Madrid, Spain
E-mail: conchi.serrano@icmm.csic.es, delmonte@icmm.csic.es
Fax: +34 913720623
Tel: +34 913349033

Abstract

Poly(octanediol-co-citrate) elastomers containing high loading of lidocaine were synthesized at temperatures below 100 °C by means of using deep eutectic mixtures of 1,8-octanediol and lidocaine. The preservation of lidocaine integrity resulted in high-capacity drug-eluting elastomers.

Graphical abstract: Synthesis of novel lidocaine-releasing poly(diol-co-citrate) elastomers by using deep eutectic solvents

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Article information

DOI
https://doi.org/10.1039/C1CC15284J
Article type
Communication
Submitted
25 Aug 2011
Accepted
09 Nov 2011
First published
22 Nov 2011

Chem. Commun., 2012,48, 579-581

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Synthesis of novel lidocaine-releasing poly(diol-co-citrate) elastomers by using deep eutectic solvents

M. C. Serrano, M. C. Gutiérrez, R. Jiménez, M. L. Ferrer and F. D. Monte, Chem. Commun., 2012, 48, 579 DOI: 10.1039/C1CC15284J

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