Issue 1, 2012
From the journal:

Chemical Communications

A carbon nanoparticle-based low-background biosensing platform for sensitive and label-free fluorescent assay of DNA methylation†

Xiangyuan Ouyang,‡a   Jinhua Liu,‡a   Jishan Li*a  and  Ronghua Yang*a  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China
E-mail: jishanli@hnu.cn, Yangrh@pku.edu.cn

Abstract

Combining a DNA intercalator, SYBR Green I, and enzyme-linkage reactions with carbon nanoparticles, a low-background biosensing platform for label-free and sensitive fluorescent assay of DNA methylation is reported.

Graphical abstract: A carbon nanoparticle-based low-background biosensing platform for sensitive and label-free fluorescent assay of DNA methylation

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Article information

DOI
https://doi.org/10.1039/C1CC15511C
Article type
Communication
Submitted
06 Sep 2011
Accepted
18 Oct 2011
First published
07 Nov 2011

Chem. Commun., 2012,48, 88-90

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A carbon nanoparticle-based low-background biosensing platform for sensitive and label-free fluorescent assay of DNA methylation

X. Ouyang, J. Liu, J. Li and R. Yang, Chem. Commun., 2012, 48, 88 DOI: 10.1039/C1CC15511C

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