Issue 3, 2012
From the journal:

Chemical Communications

Nicking enzyme based homogeneous aptasensors for amplification detection of protein†

Ai-Xian Zheng,a   Jin-Ru Wang,a   Juan Li,a   Xiao-Rong Song,a   Guo-Nan Chena  and  Huang-Hao Yang*a  

* Corresponding authors

a The Key Lab of Analysis and Detection Technology for Food Safety of the MOE, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, P. R. China
E-mail: hhyang@fio.org.cn
Fax: +86 591 22866227
Tel: +86 591 22866135

Abstract

A simple and highly sensitive homogeneous aptasensor is developed, which relies on nicking enzyme. The sensitivity of this newly proposed aptasensor is about three orders of magnitude higher than that of traditional homogeneous aptasensors. Furthermore, it is capable of detecting target protein in real samples.

Graphical abstract: Nicking enzyme based homogeneous aptasensors for amplification detection of protein

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Article information

DOI
https://doi.org/10.1039/C1CC15853H
Article type
Communication
Submitted
21 Sep 2011
Accepted
01 Nov 2011
First published
14 Nov 2011

Chem. Commun., 2012,48, 374-376

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Nicking enzyme based homogeneous aptasensors for amplification detection of protein

A. Zheng, J. Wang, J. Li, X. Song, G. Chen and H. Yang, Chem. Commun., 2012, 48, 374 DOI: 10.1039/C1CC15853H

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