Issue 23, 2012
From the journal:

Chemical Communications

Dual polarisation interferometry for real-time, label-free detection of interaction of mercury(ii) with mercury-specific oligonucleotides†

Yong Wang,ab   Yu Zheng,ab   Fan Yanga  and  Xiurong Yang*a  

* Corresponding authors

a State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China
E-mail: xryang@ciac.jl.cn
Fax: +86 431 85689278
Tel: +86 431 85262056

b Graduate School of the Chinese Academy of Sciences, Beijing 100039, China

Abstract

A real-time, label-free dual polarisation interferometry technique was used to investigate the interaction of Hg2+ with a 21-mer T-rich oligonucleotide and further construct a Hg2+ biosensor based on thymine–Hg2+–thymine coordination chemistry.

Graphical abstract: Dual polarisation interferometry for real-time, label-free detection of interaction of mercury(ii) with mercury-specific oligonucleotides

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Article information

DOI
https://doi.org/10.1039/C2CC16279B
Article type
Communication
Submitted
10 Oct 2011
Accepted
19 Jan 2012
First published
06 Feb 2012

Chem. Commun., 2012,48, 2873-2875

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Dual polarisation interferometry for real-time, label-free detection of interaction of mercury(II) with mercury-specific oligonucleotides

Y. Wang, Y. Zheng, F. Yang and X. Yang, Chem. Commun., 2012, 48, 2873 DOI: 10.1039/C2CC16279B

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