Issue 26, 2012
From the journal:

Chemical Communications

A DTTA-ligated uridine–quantum dot conjugate as a bimodal contrast agent for cellular imaging†

Junwon Park,‡a   Sankarprasad Bhuniya,‡a   Hyunseung Lee,b   Young-Woock Noh,c   Yong Taik Lim,c   Jong Hwa Jung,d   Kwan Soo Hong*bc  and  Jong Seung Kim*a  

* Corresponding authors

a Department of Chemistry, Korea University, Seoul 136-701, Korea
E-mail: jongskim@korea.ac.kr
Fax: +82-2-3290-3121

b Division of MR Research, Korea Basic Science Institute, Cheongwon 363-883, Korea

c Graduate School of Analytical Science and Technology, Chungnam National University, Daejeon 305-764, Korea

d Department of Chemistry and Research Institute of Natural Science, Gyeongsang National University, Jinju 660-701, Korea

Abstract

A uridine–quantum dot conjugate, a contrast agent for multimodal imaging, was synthesized. Its T1 relaxivity was 655 and 571.2 mM−1 s−1 per particle at 36 °C in phosphate buffered saline at 60 and 200 MHz, respectively. In vitro multimodal images confirmed its uptake by RAW 264.7 cells.

Graphical abstract: A DTTA-ligated uridine–quantum dot conjugate as a bimodal contrast agent for cellular imaging

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Article information

DOI
https://doi.org/10.1039/C2CC17555J
Article type
Communication
Submitted
03 Dec 2011
Accepted
03 Feb 2012
First published
20 Feb 2012

Chem. Commun., 2012,48, 3218-3220

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A DTTA-ligated uridine–quantum dot conjugate as a bimodal contrast agent for cellular imaging

J. Park, S. Bhuniya, H. Lee, Y. Noh, Y. T. Lim, J. H. Jung, K. S. Hong and J. S. Kim, Chem. Commun., 2012, 48, 3218 DOI: 10.1039/C2CC17555J

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