Issue 26, 2012
From the journal:

Chemical Communications

A turn-on two-photonfluorescent probe for ATP and ADP†

Alla Sreenivasa Rao,a   Dokyoung Kim,a   Hyoseok Nam,b   Hunho Jo,a   Ki Hean Kim,*b   Changill Ban*a  and  Kyo Han Ahn*a  

* Corresponding authors

a Department of Chemistry and the Center for Electro-Photo Behaviors in Advanced Molecular Systems, POSTECH, San 31, Hyoja-dong, Pohang, Republic of Korea
E-mail: ahn@postech.ac.kr

b Department of Mechanical Engineering, POSTECH, San 31, Hyoja-dong, Pohang, Republic of Korea

Abstract

An acedan derivative containing Zn(II)–DPA has been developed as a two-photon probe for nucleoside phosphates, which shows enhanced fluorescence toward ATP and ADP at physiological pH 7.4 among other competing anions including AMP; the probe is permeable to cell membranes and thus can be directly used for two-photon imaging of ATP and ADP in live cells.

Graphical abstract: A turn-on two-photon fluorescent probe for ATP and ADP

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Article information

DOI
https://doi.org/10.1039/C2CC17629G
Article type
Communication
Submitted
06 Dec 2011
Accepted
01 Feb 2012
First published
02 Feb 2012

Chem. Commun., 2012,48, 3206-3208

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A turn-on two-photon fluorescent probe for ATP and ADP

A. Sreenivasa Rao, D. Kim, H. Nam, H. Jo, K. H. Kim, C. Ban and K. H. Ahn, Chem. Commun., 2012, 48, 3206 DOI: 10.1039/C2CC17629G

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