Issue 42, 2012
From the journal:

Chemical Communications

Palladium-catalyzed direct phosphonation of azoles with dialkyl phosphites†

Chaodong Hou,ab   Yunlai Ren,b   Rui Lang,a   Xiaoxue Hu,a   Chungu Xiaa  and  Fuwei Li*a  

* Corresponding authors

a State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, China
E-mail: fuweili@licp.cas.cn
Fax: +86-931-4968129

b School of Chemical Engineering & Pharmaceutics, Henan University of Science and Technology, Luoyang, China

Abstract

The first Pd-catalyzed direct phosphonation of azoles with dialkyl phosphites has been achieved without addition of base or acid. This method involves the oxidative cleavage of C–H and P(O)–H bonds and represents an atom-efficiency alternative to the classical phosphonation of Ar–X. A PdII/PdIV mechanism has been studied and proposed.

Graphical abstract: Palladium-catalyzed direct phosphonation of azoles with dialkyl phosphites

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2CC30429E
Article type
Communication
Submitted
18 Jan 2012
Accepted
05 Apr 2012
First published
05 Apr 2012

Chem. Commun., 2012,48, 5181-5183

Permissions

Request permissions

Palladium-catalyzed direct phosphonation of azoles with dialkyl phosphites

C. Hou, Y. Ren, R. Lang, X. Hu, C. Xia and F. Li, Chem. Commun., 2012, 48, 5181 DOI: 10.1039/C2CC30429E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements