Issue 39, 2012
From the journal:

Chemical Communications

Micelles based on gold-glycopolymer complexes as new chemotherapy drug delivery agents†

Samuel Pearson,a   Wei Scaranoa  and  Martina H. Stenzel*a  

* Corresponding authors

a Centre for Advanced Macromolecular Design, University of New South Wales, Sydney, Australia
E-mail: M.Stenzel@unsw.edu.au
Fax: + 61-2-93856250
Tel: + 61-2-93854344

Abstract

Polymeric versions of deacetylated auranofin, a gold complex with a sugar ligand, were prepared by post-modifying RAFT glycopolymers. Micellisation of a block copolymer containing pendant Au(I) units produced nanoparticles with an increased anti-proliferative effect against OVCAR-3 human ovarian carcinoma cells.

Graphical abstract: Micelles based on gold-glycopolymer complexes as new chemotherapy drug delivery agents

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Article information

DOI
https://doi.org/10.1039/C2CC30510K
Article type
Communication
Submitted
22 Jan 2012
Accepted
09 Mar 2012
First published
09 Mar 2012

Chem. Commun., 2012,48, 4695-4697

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Micelles based on gold-glycopolymer complexes as new chemotherapy drug delivery agents

S. Pearson, W. Scarano and M. H. Stenzel, Chem. Commun., 2012, 48, 4695 DOI: 10.1039/C2CC30510K

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