Issue 37, 2012
From the journal:

Chemical Communications

One-pot synthesis of 4-substituted isoquinolinium zwitterionic salts by metal-free C–H bond activation†

Hong Hou,a   Yuan Zhanga  and  Chao-Guo Yan*a  

* Corresponding authors

a College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, China
E-mail: cgyan@yzu.edu.cn

Abstract

The unprecedented isoquinolinium zwitterionic salts with an unusual C-4 substitution pattern were efficiently prepared via the multicomponent reaction of in situ formed N-benzylisoquinolinium bromide with aromatic aldehydes and cyclic 1,3-dicarbonyl compounds.

Graphical abstract: One-pot synthesis of 4-substituted isoquinolinium zwitterionic salts by metal-free C–H bond activation

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Article information

DOI
https://doi.org/10.1039/C2CC30708A
Article type
Communication
Submitted
01 Feb 2012
Accepted
12 Mar 2012
First published
13 Mar 2012

Chem. Commun., 2012,48, 4492-4494

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One-pot synthesis of 4-substituted isoquinolinium zwitterionic salts by metal-free C–H bond activation

H. Hou, Y. Zhang and C. Yan, Chem. Commun., 2012, 48, 4492 DOI: 10.1039/C2CC30708A

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