Issue 32, 2012
From the journal:

Chemical Communications

Phosphate starvation as an antimicrobial strategy: the controllable toxicity of lanthanum oxide nanoparticles†

Lukas C. Gerber,a   Nadine Moser,a   Norman A. Luechinger,a   Wendelin J. Starka  and  Robert N. Grass*a  

* Corresponding authors

a Institute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, ETH Zurich, Wolfgang-Pauli-Strasse 10, 8093 Zurich, Switzerland
E-mail: robert.grass@chem.ethz.ch
Fax: +41 44 633 15 71
Tel: +41 44 633 63 34

Abstract

Lanthanum oxide nanoparticles were utilized to scavenge phosphate from microbial growth media for the use of targeted nutrient starvation as an antimicrobial strategy. Only in phosphate poor environments a toxic effect was observed. The effect was shown on Escherichia coli, Staphylococcus carnosus, Penicillium roqueforti, and Chlorella vulgaris.

Graphical abstract: Phosphate starvation as an antimicrobial strategy: the controllable toxicity of lanthanum oxide nanoparticles

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Article information

DOI
https://doi.org/10.1039/C2CC30903C
Article type
Communication
Submitted
08 Feb 2012
Accepted
01 Mar 2012
First published
01 Mar 2012

Chem. Commun., 2012,48, 3869-3871

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Phosphate starvation as an antimicrobial strategy: the controllable toxicity of lanthanum oxide nanoparticles

L. C. Gerber, N. Moser, N. A. Luechinger, W. J. Stark and R. N. Grass, Chem. Commun., 2012, 48, 3869 DOI: 10.1039/C2CC30903C

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