Issue 42, 2012

Rhodium-catalyzed oxidative C2-acylation of indoles with aryl and alkyl aldehydes

Abstract

A rhodium-catalyzed oxidative C2-acylation of indoles with aryl and alkyl aldehydes via C–H bond activation is described. The reaction is highly atom-economic and provides easy access to a wide variety of 2-aroylindoles.

Graphical abstract: Rhodium-catalyzed oxidative C2-acylation of indoles with aryl and alkyl aldehydes

Supplementary files

Article information

Article type
Communication
Submitted
23 Feb 2012
Accepted
26 Mar 2012
First published
26 Mar 2012

Chem. Commun., 2012,48, 5163-5165

Rhodium-catalyzed oxidative C2-acylation of indoles with aryl and alkyl aldehydes

B. Zhou, Y. Yang and Y. Li, Chem. Commun., 2012, 48, 5163 DOI: 10.1039/C2CC31351K

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