Issue 66, 2012
From the journal:

Chemical Communications

Positively charged silver nanoparticles and their effect on surface-enhanced Raman scattering of dye-labelled oligonucleotides†

Danny van Lierop,‡a   Željka Krpetić,‡a   Luca Guerrini,a   Iain A. Larmour,a   Jennifer A. Dougan,a   Karen Faulds*a  and  Duncan Graham*a  

* Corresponding authors

a Centre for Molecular Nanometrology, WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral St., Glasgow, UK
E-mail: Duncan.Graham@strath.ac.uk, Karen.Faulds@strath.ac.uk
Tel: +44 141 548 2507

Abstract

Improved positively charged nanoparticles are described to provide a simplified SERS substrate for DNA detection. Complete flocculation of the nanoparticles is prevented due to the controlled analyte induced aggregation. This provides a stable aggregation state which significantly extends the analysis window simplifying DNA detection by SERS.

Graphical abstract: Positively charged silver nanoparticles and their effect on surface-enhanced Raman scattering of dye-labelled oligonucleotides

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Article information

DOI
https://doi.org/10.1039/C2CC31731A
Article type
Communication
Submitted
08 Mar 2012
Accepted
10 Apr 2012
First published
30 Apr 2012

Chem. Commun., 2012,48, 8192-8194

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Positively charged silver nanoparticles and their effect on surface-enhanced Raman scattering of dye-labelled oligonucleotides

D. van Lierop, Ž. Krpetić, L. Guerrini, I. A. Larmour, J. A. Dougan, K. Faulds and D. Graham, Chem. Commun., 2012, 48, 8192 DOI: 10.1039/C2CC31731A

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