Issue 64, 2012
From the journal:

Chemical Communications

Peroxidase-mimic bismuth–gold nanoparticles for determining the activity of thrombin and drug screening†

Chia-Wen Lien,a   Chih-Ching Huang*bc  and  Huan-Tsung Chang*a  

* Corresponding authors

a Department of Chemistry, National Taiwan University, 1, Section 4, Roosevelt Road, Taipei, Taiwan
E-mail: changht@ntu.edu.tw
Fax: +886-2-3366-1171
Tel: +886-2-3366-1171

b Institute of Bioscience and Biotechnology, National Taiwan Ocean University, 2, Pei-Ning Road, Keelung, Taiwan

c Center of Excellence for Marine Bioenvironment and Biotechnology (CMBB), National Taiwan Ocean University, 2, Pei-Ning Road, Keelung, Taiwan
E-mail: huanging@ntou.edu.tw
Fax: +886-2-2462-2320
Tel: +886-2-2462-2192 ext 5517

Abstract

Fibrinogen-modified bismuth–gold nanoparticles (Fib-Bi–Au NPs) are prepared and used as enzyme mimics for the H2O2-mediated reaction with Amplex Red (AR), which is further employed for determining thrombin activity and drug screening.

Graphical abstract: Peroxidase-mimic bismuth–gold nanoparticles for determining the activity of thrombin and drug screening

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Article information

DOI
https://doi.org/10.1039/C2CC32833J
Article type
Communication
Submitted
20 Apr 2012
Accepted
21 Jun 2012
First published
21 Jun 2012

Chem. Commun., 2012,48, 7952-7954

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Peroxidase-mimic bismuth–gold nanoparticles for determining the activity of thrombin and drug screening

C. Lien, C. Huang and H. Chang, Chem. Commun., 2012, 48, 7952 DOI: 10.1039/C2CC32833J

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