Issue 71, 2012

A modular synthesis of dithiocarbamate pendant unnatural α-amino acids

Abstract

Unnatural α-amino acids containing dithiocarbamate side chains were synthesized by a one-pot reaction of in situ generated dithiocarbamate anions with sulfamidates. A wide range of these anions participated in the highly regio- and stereo-selective ring opening of sulfamidates to produce the corresponding dithiocarbamate pendant α-amino acids in high yields.

Graphical abstract: A modular synthesis of dithiocarbamate pendant unnatural α-amino acids

Supplementary files

Article information

Article type
Communication
Submitted
23 Apr 2012
Accepted
29 Jun 2012
First published
29 Jun 2012

Chem. Commun., 2012,48, 8889-8891

A modular synthesis of dithiocarbamate pendant unnatural α-amino acids

A. Saha, R. B. N. Baig, J. Leazer and R. S. Varma, Chem. Commun., 2012, 48, 8889 DOI: 10.1039/C2CC32894A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements