Polypharmacology of sulfonamides: pazopanib, a multitargeted receptor tyrosine kinase inhibitor in clinical use, potently inhibits several mammalian carbonic anhydrases†
Abstract
* Corresponding authors
a Institut des Biomolécules Max Mousseron (IBMM), UMR 5247 CNRS-UM1-UM2, Bâtiment de Recherche Max Mousseron, Ecole Nationale Supérieure de Chimie de Montpellier, 8 rue de l'Ecole Normale, 34296 Montpellier Cedex, France
b Università degli Studi di Firenze, Polo Scientifico, Laboratorio di Chimica Bioinorganica, Rm. 188, via della Lastruccia 3, Florence, Italy
c
Università degli Studi di Firenze, Polo Scientifico Dipartimento di Scienze Farmaceutiche, Florence, Italy
E-mail:
claudiu.supuran@unifi.it
J. Winum, A. Maresca, F. Carta, A. Scozzafava and C. T. Supuran, Chem. Commun., 2012, 48, 8177 DOI: 10.1039/C2CC33415A
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