GOx signaling triggered by aptamer-based ATP detection†
Abstract
Aptamer based ATP binding leads to the release of the co-factor FAD, which acts as a trigger to ‘turn-on’ the activity of apo-GOx and thus generates a measurable response.
* Corresponding authors
a
Department of Chemistry, Xavier University of Louisiana, 1 Drexel Drive, New Orleans, USA
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mali2@xula.edu
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Aptamer based ATP binding leads to the release of the co-factor FAD, which acts as a trigger to ‘turn-on’ the activity of apo-GOx and thus generates a measurable response.
S. Sitaula, S. D. Branch and M. F. Ali, Chem. Commun., 2012, 48, 9284 DOI: 10.1039/C2CC34279K
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