A two-step modular synthesis of an α-hydroxycyclopentenone and α-amido-indanones has been developed based on the Nazarov cyclization of 2-amido-1,4-pentadien-3-ones, readily accessed via formal hydroacylation of allenamides.
Y. Wu, T. Niu and F. G. West, Chem. Commun., 2012, 48, 9186 DOI: 10.1039/C2CC34644C
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