Caryl–Calkyl bond formation from Cu(ClO4)2-mediated oxidative cross coupling reaction between arenes and alkyllithium reagents through structurally well-defined Ar–Cu(iii) intermediates

Abstract

The stable and structurally well-defined Ar–Cu(III) intermediates, that are prepared almost quantitatively from the reaction of azacalix[1]arene[3]pyridines with Cu(ClO₄)₂·6H₂O under aerobic conditions, reacted smoothly with a number of alkyllithium reagents under mild conditions to form C_aryl–C_alkyl bonds.