Issue 91, 2012

Do zwitterionic species exist in the non-enzymatic peptide bond formation?

Abstract

The use of proper computational methods and models has allowed answering the controversial question of whether zwitterionic species exist in the mechanism of peptide bond synthesis in aqueous solution. In fact, the different conformations of zwitterionic species open the door to different mechanistic paths.

Graphical abstract: Do zwitterionic species exist in the non-enzymatic peptide bond formation?

Supplementary files

Article information

Article type
Communication
Submitted
26 Jul 2012
Accepted
30 Sep 2012
First published
02 Oct 2012

Chem. Commun., 2012,48, 11253-11255

Do zwitterionic species exist in the non-enzymatic peptide bond formation?

K. Świderek, I. Tuñón, S. Martí, V. Moliner and J. Bertrán, Chem. Commun., 2012, 48, 11253 DOI: 10.1039/C2CC35409H

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