A new internal charge transfer (ICT) fluorescent probe for highly selective and sensitive monitoring of H2S has been developed. The design takes advantage of the facile reduction of non-fluorescent hydroxyamine naphthalimide by H2S to highly fluorescent amine naphthalimide. It has been demonstrated that the probe is able to detect H2S at submicromolar concentrations in cells.
W. Xuan, R. Pan, Y. Cao, K. Liu and W. Wang, Chem. Commun., 2012, 48, 10669 DOI: 10.1039/C2CC35602C
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