Issue 87, 2012
From the journal:

Chemical Communications

Sensitive point-of-care monitoring of HIV related DNA sequences with a personal glucometer†

Jin Xu,a   Bingying Jiang,*b   Jiaqing Xie,b   Yun Xiang,*a   Ruo Yuana  and  Yaqin Chaia  

* Corresponding authors

a Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China
E-mail: yunatswu@swu.edu.cn
Fax: +86-23-68252277
Tel: +86-23-68253172

b School of Chemistry and Chemical Engineering, Chongqing University of Technology, Chongqing 400054, P. R. China
E-mail: jiangby@cqut.edu.cn
Fax: +86-23-68667675
Tel: +86-23-68667675

Abstract

The hybridizations between the HIV target DNA and the capture probes as well as the signal probes conjugated to the multi-invertase/nanoparticle composites lead to the conversion of sucrose to glucose, which is monitored by the personal glucometer and provides quantitative digital readings for point-of-care diagnosis of HIV DNA fragments.

Graphical abstract: Sensitive point-of-care monitoring of HIV related DNA sequences with a personal glucometer

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Article information

DOI
https://doi.org/10.1039/C2CC35941C
Article type
Communication
Submitted
16 Aug 2012
Accepted
11 Sep 2012
First published
11 Sep 2012

Chem. Commun., 2012,48, 10733-10735

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Sensitive point-of-care monitoring of HIV related DNA sequences with a personal glucometer

J. Xu, B. Jiang, J. Xie, Y. Xiang, R. Yuan and Y. Chai, Chem. Commun., 2012, 48, 10733 DOI: 10.1039/C2CC35941C

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