Issue 85, 2012
From the journal:

Chemical Communications

A reagentless and reusable electrochemical DNA sensor based on target hybridization-induced stem-loop probe formation†

Zhi-gang Yuab  and  Rebecca Y. Lai*b  

* Corresponding authors

a Key Laboratory of Green Chemical Engineering and Technology of College of Heilongjiang Province, College of Chemical and Environmental Engineering, Harbin University of Science and Technology, Harbin 150040, P. R. China
E-mail: yzgyh@126.com

b University of Nebraska-Lincoln, 651 Hamilton Hall, Lincoln, NE 68588-0304, USA
E-mail: rlai2@unl.edu
Fax: +1 402 472 9402
Tel: +1 402 472 5340

Abstract

We report a reagentless and reusable electrochemical DNA sensor that exploits competitive binding and target hybridization-induced change in the signalling probe conformation for robust detection of a target DNA sequence.

Graphical abstract: A reagentless and reusable electrochemical DNA sensor based on target hybridization-induced stem-loop probe formation

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Article information

DOI
https://doi.org/10.1039/C2CC35985E
Article type
Communication
Submitted
18 Aug 2012
Accepted
05 Sep 2012
First published
06 Sep 2012

Chem. Commun., 2012,48, 10523-10525

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A reagentless and reusable electrochemical DNA sensor based on target hybridization-induced stem-loop probe formation

Z. Yu and R. Y. Lai, Chem. Commun., 2012, 48, 10523 DOI: 10.1039/C2CC35985E

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