Issue 95, 2012
From the journal:

Chemical Communications

Imaging acidosis in tumors using a pH-activated near-infrared fluorescence probe†

Lu Wang,a   Xiao Zhu,a   Cheng Xie,a   Ning Ding,a   Xiaofu Weng,b   Weiyue Lu,a   Xunbin Wei*b  and  Cong Li*a  

* Corresponding authors

a Key Laboratory of Smart Drug Delivery, Ministry of Education & PLA, School of Pharmacy, Fudan University, 826 Zhangheng Rd, Shanghai 201203, China
E-mail: congli@fudan.edu.cn
Fax: +86 21 5198 0100
Tel: +86 21 5198 0100

b Med-X Research Institute and School of Biomedical Engineering, Shanghai Jiao Tong University, 1954 Huashang Rd, Shanghai 200030, China
E-mail: xwei01@sjtu.edu.cn
Fax: +86 21 62933072
Tel: +86 21 62932302

Abstract

A novel pH activatable near-infrared fluorescence probe was developed, which successfully visualized acidosis in tumors. This probe holds promise to non-invasively predict the tumor metastasis potential and evaluate the therapeutic response.

Graphical abstract: Imaging acidosis in tumors using a pH-activated near-infrared fluorescence probe

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Article information

DOI
https://doi.org/10.1039/C2CC36488C
Article type
Communication
Submitted
05 Sep 2012
Accepted
12 Oct 2012
First published
15 Oct 2012

Chem. Commun., 2012,48, 11677-11679

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Imaging acidosis in tumors using a pH-activated near-infrared fluorescence probe

L. Wang, X. Zhu, C. Xie, N. Ding, X. Weng, W. Lu, X. Wei and C. Li, Chem. Commun., 2012, 48, 11677 DOI: 10.1039/C2CC36488C

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