Issue 95, 2012
From the journal:

Chemical Communications

Exonuclease-aided amplification for label-free and fluorescence turn-on DNA detection based on aggregation-induced quenching†

Enguo Ju,ab   Xinjian Yang,ab   Youhui Lin,ab   Fang Pu,a   Jinsong Ren*a  and  Xiaogang Qu*a  

* Corresponding authors

a State Key Laboratory of Rare Earth Resource Utilization and Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China
E-mail: jren@ciac.jl.cn, xqu@ciac.jl.cn

b Graduate School of the Chinese Academy of Sciences, Beijing, China

Abstract

A facile, universal and label-free fluorescence turn-on amplification strategy for the detection of DNA has been reported, which can achieve ultralow femtomolar detection of a target gene sequence with high selectivity.

Graphical abstract: Exonuclease-aided amplification for label-free and fluorescence turn-on DNA detection based on aggregation-induced quenching

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Article information

DOI
https://doi.org/10.1039/C2CC37039E
Article type
Communication
Submitted
28 Sep 2012
Accepted
18 Oct 2012
First published
18 Oct 2012

Chem. Commun., 2012,48, 11662-11664

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Exonuclease-aided amplification for label-free and fluorescence turn-on DNA detection based on aggregation-induced quenching

E. Ju, X. Yang, Y. Lin, F. Pu, J. Ren and X. Qu, Chem. Commun., 2012, 48, 11662 DOI: 10.1039/C2CC37039E

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