Issue 36, 2012

Switchable boronate affinity materials for thermally modulated capture, separation and enrichment of cis-diol biomolecules

Abstract

A new thermoresponsive boronate affinity chromatographic material, P(N-isopropylacrylamide-4-vinylphenylboronic acid) P(NIPAAm-co-VPBA) grafted silica featuring a thermally switchable property, was prepared and successfully employed for the specific capture–release of cis-diol biomolecules with simpler adjustment to the temperature instead of the conventional need to change the pH of the mobile phase.

Graphical abstract: Switchable boronate affinity materials for thermally modulated capture, separation and enrichment of cis-diol biomolecules

Supplementary files

Article information

Article type
Communication
Submitted
04 Jun 2012
Accepted
19 Jul 2012
First published
20 Jul 2012

J. Mater. Chem., 2012,22, 18753-18756

Switchable boronate affinity materials for thermally modulated capture, separation and enrichment of cis-diol biomolecules

Z. Liu, K. Ullah, L. Su, F. Lv, Y. Deng, R. Dai, Y. Li and Y. Zhang, J. Mater. Chem., 2012, 22, 18753 DOI: 10.1039/C2JM33578F

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